Assignment: Drug Interactions with Antidepressants Essay
Assignment: Drug Interactions with Antidepressants Essay
WE WRITE ESSAYS FOR STUDENTS
Tell us about your assignment and we will find the best writer for your project
Write My Essay For MeMost antidepressants drug to drug interactions occur by impairing drug elimination by interfering with hepatic metabolism, transcellular transport, or renal excretion (Bleakley, 2016). MAOIs are associated with some of the most significant drug interactions of all the antidepressants with adverse symptoms, including hypertensive crisis (Bleakley, 2016). TCAs have a narrow therapeutic index and potential adverse effects of cardiotoxicity. Selective serotonin reuptake inhibitors (SSRIs) have drug interactions with cytochrome P450 enzymes and inhibit the metabolism of other antidepressants.
Click here to ORDER an A++ paper from our Verified MASTERS and DOCTORATE WRITERS: Assignment: Drug Interactions with Antidepressants Essay
Bupropion has been shown to have potential significant drug interactions when administered with other antidepressants (Hoffelt & Gross, 2016). Venlafaxine and bupropion are administered in combination for treatment-resistant depression. Bupropion inhibits
Assignment Drug Interactions with Antidepressants Essay
CYP2D6, which is the enzyme that metabolizes Venlafaxine, and this may result in increased side effects such as anxiety and Serotonin Syndrome (Hoffelt & Gross, 2016). In addition, there is a significant drug to drug interaction between Duloxetine and Paroxetine, which results in an increased concentration of Duloxetine (Hoffelt & Gross, 2016). A drug interaction also occurs between Duloxetine and Fluvoxamine, which increases Duloxetine concentration.
Administering a combination of SSRIs may result in Serotonin Syndrome, which manifests with mild to life-threatening symptoms. SSRIs increase the level of serotonin and act against directs agonists of postsynaptic serotonin receptors in the central nervous system, and this results in serotonin toxicity (Bleakley, 2016). Increased serotoninergic neurotransmission can result in an altered mental status, altered neuromuscular excitability, autonomic instability, and hemodynamic changes such as hypertension and tachycardia (Bleakley, 2016). Drugs that have been associated with serotonin syndrome when combined with SSRIs or other serotonergic enhancing antidepressants include buspirone, lithium, linezolid, fentanyl, pethidine, and tramadol.
Click here to ORDER an A++ paper from our MASTERS and DOCTORATE WRITERS: Assignment: Drug Interactions with Antidepressants Essay
Use the following coupon code :
SAVE15
Assignment: Drug Interactions with Antidepressants Essay
DO MY HOMEWORK NOW!Write my Essay. Premium essay writing services is the ideal place for homework help or essay writing service. if you are looking for affordable, high quality & non-plagiarized papers, click on the button below to place your order. Provide us with the instructions and one of our writers will deliver a unique, no plagiarism, and professional paper.
Get help with your toughest assignments and get them solved by a Reliable Custom Papers Writing Company. Save time, money and get quality papers. Buying an excellent plagiarism-free paper is a piece of cake!
All our papers are written from scratch. We can cover any assignment/essay in your field of study.
